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发表于:2020-02-07 20:18:19
FDA strengthens warning label for certain anti-inflammatory drugs(Reuters) - The U.S. food and Drug Administration said it was strengthening an existing warning label that non-aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke. NSA

IDs are used to treat pain and fever from medical conditions such as arthritis, menstrual cramps, headaches, colds, and the flu, and some of the better-known medicines on the market includ

e ibuprofen, naproxen,

diclofenac and celecoxib, all of which carry FDA warning labels. The agency said it would require up

dates to the labels of prescription and

over-the-counter (OTC) non-aspirin NSAIDs,

both of

which already carry information on heart attack and stroke risk. The revised labels will reflect that the risk of heart complications can occur as early as the first wee

ks of using an NSAID and increases at higher doses and depending on duration of use, the FDA said. The new labels will also reflect that the drugs increase the risk of heart failure, irrespective of whether patients have a history

of, or risk factors for, heart disease. The agency said it would also require labels to reflect that patients who take NSAIDs after a first heart attack are more likely to die in the first year after the a

ttac

k than those who do not. (1.usa.gov/1HRh0zq)

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